Zofran is used for:

Preventing nausea and vomiting due to cancer chemotherapy or surgery. It may also be used for other conditions as determined by your doctor.

Zofran is a serotonin 5-HT₃ receptor blocker. It works by blocking a chemical thought to be a cause of nausea and vomiting in certain situations (eg, chemotherapy).

Do NOT use Zofran if:

• you are allergic to any ingredient in Zofran

Contact your doctor or health care provider right away if any of these apply to you.

Before using Zofran :

Some medical conditions may interact with Zofran. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have liver problems

Some MEDICINES MAY INTERACT with Zofran. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Antineoplastic agents (eg, cyclophosphamide) because the effectiveness of these medicines may be decreased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Zofran may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Zofran :

Use Zofran as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Zofran is usually administered as an injection at your doctor's office, hospital, or clinic. If you are using Zofran at home, carefully follow the injection procedures taught to you by your health care provider.
• If Zofran contains particles or is discolored, or if the vial or container is cracked or damaged in any way, do not use it.
• Keep this product, as well as syringes and needles, out of the reach of children. Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor or pharmacist to explain local regulations for proper disposal.
• It is important that Zofran be given prior to cancer chemotherapy as directed. If you miss a dose of Zofran , contact your doctor or pharmacist.

Ask your health care provider any questions you may have about how to use Zofran.

Important safety information:

• Zofran may cause drowsiness or dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Zofran. Using Zofran alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
• Use Zofran with extreme caution in CHILDREN younger than 4 months of age. Safety and effectiveness in this age group have not been confirmed.
• PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Zofran , discuss with your doctor the benefits and risks of using Zofran during pregnancy. It is unknown if Zofran is excreted in breast milk. If you are or will be breast-feeding while you are using Zofran , check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Zofran :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; headache; irritation, redness, pain, or burning at the site of injection; tiredness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; fever; skin tingling or numbness; trouble urinating; vision changes or loss.

What is the shelf life of the pills?

• The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.